N-(p-Coumaroyl) Serotonin
Cat. No.：YN440231
CAS No. ：68573-24-0
规格
价格(RMB)
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| 产品名称: | N-(p-Coumaroyl) Serotonin |
| CAS No.: | 68573-24-0 |
| Chemical Name: | N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxyphenyl)-2-propenamide |
| Synonyms: | p-coumaroylserotonin |
| 分子量: | 322.36 |
| 分子式: | C₁₉H₁₈N₂O₃ |
| SMILES: | O=C(NCCC1=CNC2=C1C=C(O)C=C2)/C=C/C3=CC=C(O)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | N-(p-Coumaroyl) Serotonin 是一种从红花种子中分离出来的多酚，具有抗氧化、抗动脉粥样硬化和抗炎特性。N-(p-Coumaroyl) Serotonin 可降低肌浆网中 PDGF 诱导的对中PDGFR酪氨酸磷酸化和 Ca2+释放的作用。N-(p-Coumaroyl) Serotonin 可改善动脉粥样硬化和主动脉壁膨大，常用于动脉粥样硬化的研究。 |
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Katsuda, S., Suzuki, K., Koyama, N., et al.Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbitsHypertens. Res.32(11),944-949(2009)
Watanabe, M.Antioxidative phenolic compounds from Japanese barnyard millet (Echinochloa utilis) grainsJ. Agric. Food Chem.47(11),4500-4505(1999)
Koyama, N., Kuribayashi, K., Seki, T., et al.Serotonin derivatives, major safflower (Carthamus tinctorius L.) seed antioxidants, inhibit low-density lipoprotein (LDL) oxidation and atherosclerosis in apolipoprotein E-deficient miceJ. Agric. Food Chem.54(14),4970-4976(2015)
Kawashima, S., Hayashi, M., Takii, T., et al.Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-α, IL-1α, IL-1β, and IL-6 by endotoxin-stimulated human blood monocytesJ. Interferon Cytokine Res.18(6),423-428(1998)
Takii, T., Hayashi, M., Hiroma, H., et al.Serotonin derivative, N-(p-coumaroyl)serotonin, isolated from safflower (Carthamus tinctorius L.) oil cake augments the proliferation of normal human and mouse fibroblasts in synergy with basic fibroblast growth factor (bFGF) or epigermal growth factor (EGF)J. Biochem.125(5),910-915(1999)
Takimoto, T., Suzuki, K., Arisaka, H., et al.Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cellsMol. Nutr. Food Res.55(10),1561-1571(2011)
