TAK-593
Cat. No.:YN440329
产品名称: | TAK-593 |
CAS No.: | 1005780-62-0 |
Chemical Name: | |
Synonyms: | |
分子量: | 445.47 |
分子式: | C₂₃H₂₃N₇O₃ |
SMILES: | O=C(C1=CC(C)=NN1C)NC2=CC(OC3=NN4C(C=C3)=NC(NC(C5CC5)=O)=C4)=CC=C2C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TAK-593是有效的VEGFR2和PDGFR抑制剂,对VEGFR1, VEGFR2, VEGFR3, PDFGRα 和 PDFGRβ 的IC50值分别为3.2,0.95,1.1,4.3 和 13 nM。 |
IC50和靶点: | [{name:"VEGFR1:3.2 nM (IC50)"},{name: "VEGFR2:0.95 nM (IC50)"},{name: "VEGFR3:1.1 nM (IC50)"},{name: "PDGFRα:4.3 nM (IC50)"},{name: "PDGFRβ:13 nM (IC50)"},{name: "PDGFRαV561D:1 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |