NVP-ACC789
Cat. No.：YN440391
CAS No. ：300842-64-2
规格
价格(RMB)
库存
| 产品名称: | NVP-ACC789 |
| CAS No.: | 300842-64-2 |
| Chemical Name: | N-(3-bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine |
| Synonyms: | ACC-789; ZK202650 |
| 分子量: | 405.29 |
| 分子式: | C₂₁H₁₇BrN₄ |
| SMILES: | CC1=CC=C(NC2=NN=C(CC3=CC=NC=C3)C4=C2C=CC=C4)C=C1Br |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NVP-ACC789 是 人VEGFR-1，VEGFR-2(鼠VEGFR-2)，VEGFR-3和PDGFR-β的抑制剂，IC50值分别为 0.38，0.02 (0.23)，0.18 和 1.4 μM。 |
| IC50和靶点: | [{name:"VEGFR-2:0.02 μM (IC50)"},{name: "VEGFR-1:0.38 μM (IC50)"},{name: "mVEGFR-2:0.23 μM (IC50)"},{name: "VEGFR-3:0.18 μM (IC50)"},{name: "PDGFR-β:1.4 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tille, J.C., Wood, J., Mandriota, S.J., et al.Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basic fibroblast growth factor-induced angiogenesis in vivo and in vitroJ. Pharmacol. Exp. Ther.299(3),1073-1085(2001)
