Trapidil
Cat. No.：YN440418
CAS No. ：15421-84-8
规格
价格(RMB)
库存
| 产品名称: | Trapidil |
| CAS No.: | 15421-84-8 |
| Chemical Name: | N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-α]pyrimidin-7-amine |
| Synonyms: | 唑嘧胺; AR-12008 |
| 分子量: | 205.26 |
| 分子式: | C₁₀H₁₅N₅ |
| SMILES: | CC1=NC2=NC=NN2C(N(CC)CC)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trapidil是一种血管扩张剂，是一种抗血小板药物, 具有特异性的血小板衍生生长因子。 |
| IC50和靶点: | |
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Kuratsu, J., and Ushio, Y.Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitroJ. Neurosurg.73(3),436-440(1990)
Hoshiya, M., and Awazu, M.Trapidil inhibits platelet-derived growth factor-stimulated mitogen-activated protein kinase cascadeHypertension31(2),665-671(1998)
Mazurov, A.V., Yu, M., Leytin, V.L., et al.Decrease of platelet aggregation and spreading via inhibition of the cAMP phosphodiesterase by trapidilFEBS Lett.172(2),167-171(1984)
Liu, M.W., Roubin, G.S., Robinson, K.A., et al.Trapidil in preventing restenosis after balloon angioplasty in the atherosclerotic rabbitCirculation81(3),1089-1093(1990)
