Sennoside B
Cat. No.:YN440423
产品名称: | Sennoside B |
CAS No.: | 128-57-4 |
Chemical Name: | (9R,9'S)-5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-bianthracene]-2,2'-dicarboxylic acid |
Synonyms: | 番泻苷 B |
分子量: | 862.74 |
分子式: | C₄₂H₃₈O₂₀ |
SMILES: | O[C@@H]1[C@@H](O)[C@H](OC2=C(C(C(C(O)=CC(C(O)=O)=C3)=C3[C@]4([C@@]5(C(C=CC=C6O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)=C6C(C8=C5C=C(C(O)=O)C=C8O)=O)[H])[H])=O)C4=CC=C2)O[C@H](CO)[C@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Sennoside B 是一种蒽醌苷,在番泻叶 (Cassia angustifolia) 的叶子和豆荚中大量发现。Sennoside B 可通过与 PDGF-BB 及其受体结合并下调 PDGFR-β 信号传导途径来抑制 PDGF 刺激的细胞增殖。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Franz, G.The senna drug and its chemistryPharmacology47(Suppl 1),2-6(1993)
Hwang, I.Y., and Jeong, C.S.Gastroprotective activities of sennoside A and sennoside B via the up-regulation of prostaglandin E2 and the inhibition of H+/K+-ATPaseBiomol. Ther. (Seoul)23(5),458-464(2015)