OSU-03012
Cat. No.：YN420051
CAS No. ：742112-33-0
规格
价格(RMB)
库存
| 产品名称: | OSU-03012 |
| CAS No.: | 742112-33-0 |
| Chemical Name: | 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide |
| Synonyms: | AR-12 |
| 分子量: | 460.45 |
| 分子式: | C₂₆H₁₉F₃N₄O |
| SMILES: | O=C(CN)NC1=CC=C(C=C1)N2N=C(C=C2C3=CC=C4C5=CC=CC=C5C=CC4=C3)C(F)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | OSU-03012 是一种可以通透血脑屏障的PDK-1抑制剂，IC50为 5 μM。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
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Zhu, J., Huang, J.W., Tseng, P.H., et al.From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitorsCancer Res.64,4309-4318(2004)
Kucab, J.E., Lee, C., Chen, C.S., et al.Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumorsBreast Cancer Res.7(5),R796-R807(2004)
