BX-912
Cat. No.：YN420067
CAS No. ：702674-56-4
规格
价格(RMB)
库存
| 产品名称: | BX-912 |
| CAS No.: | 702674-56-4 |
| Chemical Name: | N-[3-[[5-bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide |
| Synonyms: | N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-yl)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide;BX-912;1-PYRROLIDINECARBOXAMIDE, N-[3-[[5-BROMO-4-[[2-(1H-IMIDAZOL-4-YL)ETHYL]AMINO]-2-PYRIMIDINYL]AMINO]PHENYL]-;BX912;N-[3-[[5-bromo-4-[2-(1H-imidaz |
| 分子量: | 471.35 |
| 分子式: | C₂₀H₂₃BrN₈O |
| SMILES: | BrC1=C(NCCC2=CNC=N2)N=C(NC3=CC(NC(N4CCCC4)=O)=CC=C3)N=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BX-912 是一种直接的，选择性的，ATP 竞争性的PDK1抑制剂 (IC50=26 nM)。BX-912 阻断肿瘤细胞 PDK1/Akt 信号转导，抑制多种肿瘤细胞株的锚定依赖性生长或诱导凋亡。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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