GSK2334470
Cat. No.:YN420196
产品名称: | GSK2334470 |
CAS No.: | 1227911-45-6 |
Chemical Name: | (3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide |
Synonyms: | GSK2334470;GSK-2334470;GSK 2334470 |
分子量: | 462.59 |
分子式: | C₂₅H₃₄N₈O |
SMILES: | O=C([C@@H]1CN(C2=NC(NC)=NC(C3=CC4=C(C=C3)C(N)=NN4)=C2)[C@H](C)CC1)NC5CCCCC5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GSK2334470是高效特异性的PDK1抑制剂,IC50值为10 nM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Najafov, A., Sommer, E.M., Axten, J.M., et al.Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1Biochem. J.433(2),357-369(2011)