TG100-115
Cat. No.:YN420018
产品名称: | TG100-115 |
CAS No.: | 677297-51-7 |
Chemical Name: | 3,3'-(2,4-Diamino-6,7-pteridinediyl)bis-phenol; TG 100115; 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine |
Synonyms: | TG100115; TG100 115 |
分子量: | 346.34 |
分子式: | C₁₈H₁₄N₆O₂ |
SMILES: | NC1=C(C(N=C2C3=CC(O)=CC=C3)=NC(N)=N1)N=C2C4=CC(O)=CC=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TG100-115 是一种选择性的PI3Kγ/PI3Kδ抑制剂,IC50分别为 83 和 235 nM。 |
IC50和靶点: | [{name:"PI3Kδ:235 nM (IC50)"},{name: "PI3Kγ:83 nM (IC50)"}] |
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Doukas, J., et al.: Proc. Natl. Acad. Sci. USA, 103, 19866 (2006)
Palanki, M.S., et al.: J. Med. Chem., 50, 4279 (2007)