AZD3458
Cat. No.：YN420088
CAS No. ：2132961-46-5
规格
价格(RMB)
库存
| 产品名称: | AZD3458 |
| CAS No.: | 2132961-46-5 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 433.54 |
| 分子式: | C₂₀H₂₃N₃O₄S₂ |
| SMILES: | O=C1N([C@@H](C)C2CC2)CC3=CC(C4=C(C)N=C(NC(C)=O)S4)=CC(S(=O)(C)=O)=C31 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD3458 是一种有效的选择性PI3Kγ抑制剂，抑制PI3Kγ,PI3Kα,PI3Kβ, 和PI3Kδ，pIC50分别为 9.1, 5.1, <4.5, 和 6.5。 |
| IC50和靶点: | [{name:"PI3Kγ:9.1 (pIC50)"},{name: "PI3Kα:5.1 (pIC50)"},{name: "PI3Kβ:4.5 (pIC50)"},{name: "PI3Kδ:6.5 (pIC50)"},{name: "PI3KC2α:5 (pIC50)"},{name: "PI3KC2β:7.5 (pIC50)"},{name: "PI3KC2γ:5.5 (pIC50)"},{name: "PI3KC3:5.1 (pIC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pemberton, N., et al.: J. Med. Chem., 61, 5435-5441 (2018)
