TG 100713
Cat. No.：YN420167
CAS No. ：925705-73-3
规格
价格(RMB)
库存
| 产品名称: | TG 100713 |
| CAS No.: | 925705-73-3 |
| Chemical Name: | 3-(2,4-diamino-6-pteridinyl)-phenol |
| Synonyms: | TG100713 |
| 分子量: | 254.25 |
| 分子式: | C₁₂H₁₀N₆O |
| SMILES: | OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TG 100713 是PI3K的抑制剂，抑制PI3Kδ，γ，α和β的IC50值分别为24、50、165 和 215 nM。 |
| IC50和靶点: | [{name:"PI3Kδ:24 nM (IC50)"},{name: "PI3Kγ:50 nM (IC50)"},{name: "PI3Kα:165 nM (IC50)"},{name: "PI3Kβ:215 nM (IC50)"}] |
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Doukas, J., Wrasidlo, W., Noronha, G., et al.Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injuryProc. Natl. Acad. Sci. USA103(52),19866-19871(2006)
Vargas, B., Giacobbi, N.S., Sanyal, A., et al.Inhibitors of signaling pathways that block reversal of HIV-1 latencyAntimicrob. Agents Chemother.63(2),e01744-01718(2019)
