AS-604850
Cat. No.：YN420170
CAS No. ：648449-76-7
规格
价格(RMB)
库存
| 产品名称: | AS-604850 |
| CAS No.: | 648449-76-7 |
| Chemical Name: | 5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione |
| Synonyms: | 5-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮 |
| 分子量: | 285.22 |
| 分子式: | C₁₁H₅F₂NO₄S |
| SMILES: | O=C(NC/1=O)SC1=C\C2=CC=C(OC(F)(F)O3)C3=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AS-604850 是一种有效的，具有选择性的和 ATP 竞争性的PI3Kγ抑制剂，IC50值为 0.25 μM，Ki值为 0.18 μM。AS-604850 是PI3Kγ的同工型选择性抑制剂，对PI3Kγ的选择性是 PI3Kδ/β 的 30 倍以上，是 PI3Kα 的 18 倍以上。 |
| IC50和靶点: | [{name:"PI3Kγ:0.25 μM (IC50)"},{name: "PI3Kγ:0.18 μM (Ki)"},{name: "PI3Kα:4.5 μM (IC50)"}] |
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| Solvent & Solubility: |
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