Buparlisib Hydrochloride
Cat. No.：YN420199
CAS No. ：1312445-63-8
规格
价格(RMB)
库存
| 产品名称: | Buparlisib Hydrochloride |
| CAS No.: | 1312445-63-8 |
| Chemical Name: | |
| Synonyms: | BKM120 Hydrochloride; NVP-BKM120 Hydrochloride |
| 分子量: | 446.85 |
| 分子式: | C₁₈H₂₂ClF₃N₆O₂ |
| SMILES: | NC(N=C1)=CC(C(F)(F)F)=C1C2=NC(N3CCOCC3)=NC(N4CCOCC4)=C2.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Buparlisib Hydrochloride (BKM120 Hydrochloride) 是一种 pan-class IPI3K抑制剂，作用于p110α/p110β/p110δ/p110γ，IC50分别为 52 nM/166 nM/116 nM/262 nM。 |
| IC50和靶点: | [{name:"p110α:52 nM (IC50)"},{name: "p110β:166 nM (IC50)"},{name: "p110δ:116 nM (IC50)"},{name: "p110γ:262 nM (IC50)"},{name: "Vps34:2.4 μM (IC50)"},{name: "p110α-H1047R:58 nM (IC50)"},{name: "p110α-E545K:99 nM (IC50)"},{name: "mTOR:4.6 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
