HS-173
Cat. No.：YN420228
CAS No. ：1276110-06-5
规格
价格(RMB)
库存
| 产品名称: | HS-173 |
| CAS No.: | 1276110-06-5 |
| Chemical Name: | 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-imidazo[1,2-a]pyridine-3-carboxylic acid, ethyl ester |
| Synonyms: | HS173,HS 173 |
| 分子量: | 422.46 |
| 分子式: | C₂₁H₁₈N₄O₄S |
| SMILES: | O=C(C1=CN=C2C=CC(C3=CC(NS(=O)(C4=CC=CC=C4)=O)=CN=C3)=CN21)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | HS-173 是一种新颖的PI3K抑制剂，常用于癌症研究。 |
| IC50和靶点: | [{name:"PI3Kα:0.8 nM (IC50)"}] |
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| Solvent & Solubility: |
Kim, O., Jeong, Y., Lee, H., et al.Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesisJ. Med. Chem.54(7),2455-2466(2011)
Lee, H., Jung, K.H., Jeong, Y., et al.HS-173, a novel phosphatidylinositol 3-kinase (PI3K) inhibitor, has anti-tumor activity through promoting apoptosis and inhibiting angiogenesisCancer Lett.328(1),152-159(2013)
Son, M.K., Ryu, Y.L., Jung, K.H., et al.HS-173, a novel PI3K inhibitor, attenuates the activation of hepatic stellate cells in liver fibrosisSci. Rep.3:3470,(2013)
