Pictilisib dimethanesulfonate
Cat. No.：YN420270
CAS No. ：957054-33-0
规格
价格(RMB)
库存
| 产品名称: | Pictilisib dimethanesulfonate |
| CAS No.: | 957054-33-0 |
| Chemical Name: | 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidine Methanesulfonate; |
| Synonyms: | GDC-0941 dimethanesulfonate; GDC-0941 2 MeSO3H salt |
| 分子量: | 705.85 |
| 分子式: | C₂₅H₃₅N₇O₉S₄ |
| SMILES: | O=S(N1CCN(CC1)CC2=CC3=C(S2)C(N4CCOCC4)=NC(C5=CC=CC6=C5C=NN6)=N3)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) 是一种有效的PI3Kα/δ抑制剂，IC50值为 3 nM；对 p110β 和 p110γ具有适度的选择性。 |
| IC50和靶点: | [{name:"p110α:3 nM (IC50)"},{name: "p110β:33 nM (IC50)"},{name: "p110δ:3 nM (IC50)"},{name: "p110γ:75 nM (IC50)"},{name: "p110α-H1047R:3 nM (IC50)"},{name: "p110α-E545K:3 nM (IC50)"},{name: "DNA-PK:1.23 μM (IC50)"},{name: "mTOR:0.58 μM (Ki)'}, 'Autophagy'] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
