H-89
Cat. No.:YN440355
产品名称: | H-89 |
CAS No.: | 127243-85-0 |
Chemical Name: | N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide; |
Synonyms: | Protein kinase inhibitor H-89 |
分子量: | 446.36 |
分子式: | C₂₀H₂₀BrN₃O₂S |
SMILES: | O=S(C1=CC=CC2=C1C=CN=C2)(NCCNC/C=C/C3=CC=C(Br)C=C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | H-89 是一种有效、选择性的 cAMP 依赖性protein kinase A抑制剂,IC50值为 48 nM,对 PKG,PKC,Casein Kinase 和其他激酶的抑制作用很弱。 |
IC50和靶点: | |
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Solvent & Solubility: |
Chijiwa, T. et al.: J. Bio. Chem., 265 (9), 5267-5272 (1990)