Warangalone
Cat. No.:YN440426
产品名称: | Warangalone |
CAS No.: | 4449-55-2 |
Chemical Name: | 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-10-(3-methyl-2-buten-1-yl)-2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one; Scandenone; Scandenolone; Warangalon |
Synonyms: | 攀登鱼藤异黄酮; Scandenolone |
分子量: | 404.46 |
分子式: | C₂₅H₂₄O₅ |
SMILES: | O=C1C(C(O)=C(C=CC(C)(C)O2)C2=C3C/C=C(C)\C)=C3OC=C1C4=CC=C(O)C=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Warangalone 是抗疟疾化合物,能够抑制3D7(氯喹敏感) 和K1(氯喹耐药) 寄生虫的生长,IC50值分别为 4.8 μg/mL 和 3.7 μg/mL。 Warangalone 还可以抑制环 AMP 依赖性蛋白激酶催化亚基 (cAK),其IC50值为 3.5 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Tati Herlina, et al.: Phytochemistry. 1997 Mar
44(5):787-96