Bilobetin
Cat. No.:YN440428
产品名称: | Bilobetin |
CAS No.: | 521-32-4 |
Chemical Name: | 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Synonyms: | 白果素 |
分子量: | 552.48 |
分子式: | C₃₁H₂₀O₁₀ |
SMILES: | O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C4=CC(C5=CC(C6=C(O)C=C(O)C=C6O5)=O)=CC=C4OC)C(O)=CC(O)=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bilobetin 是一种Ginkgo biloba活性成分,可以降低血脂,改善胰岛素的作用。 Bilobetin 改善胰岛素抵抗,增加肝脏对脂质的吸收和氧化,降低极低密度脂蛋白甘油三酯分泌和血液甘油三酯水平,增强组织中 β-氧化的酶的表达和活性,并减弱甘油三酯及其代谢产物的积累。Bilobetin 还增加了PPARα的磷酸化,核转位和活性,同时伴随着 cAMP 水平和PKA活性的升高。 |
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Li, M., Li, B., Xia, Z.-M., et al.Anticancer effects of five biflavonoids from Ginkgo Biloba L. male flowers in vitroMolecules24(8),E1496(2019)
Wang, C.G., Yao, W.N., Ahang, B., et al.Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migrationBioorg. Med. Chem. Lett.28(14),2413-2417(2018)
Sirimangkalakitti, N., Juliawaty, L.D., Hakim, E.H., et al.Naturally occurring biflavonoids with amyloid β aggregation inhibitory activity for development of anti-Alzheimer agentBioorg. Med. Chem. Lett.29(15),1994-1997(2019)