D-erythro-Sphingosine
Cat. No.：YN310036
CAS No. ：123-78-4
| 产品名称: | D-erythro-Sphingosine |
| CAS No.: | 123-78-4 |
| Chemical Name: | 2S-amino-4E-octadecene-1,3R-diol |
| Synonyms: | 鞘氨醇; Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine |
| 分子量: | 299.49 |
| 分子式: | C₁₈H₃₇NO₂ |
| SMILES: | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | D-erythro-Sphingosine (Erythrosphingosine) 是一种非常有效的p32激酶活化剂，EC50为 8 μM。D-erythro-Sphingosine 抑制蛋白激酶 C (PKC)。D-erythro-Sphingosine (Erythrosphingosine) 也是一种PP2A激活剂。 |
| IC50和靶点: | [{name:"p32:8 μM (EC50)'}, 'PKC', 'PP2A', 'Human Endogenous Metabolite', 'Microbial Metabolite'] |
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| Solvent & Solubility: |
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Ishii, I., Fukushima, N., Ye, X., et al.Lysophospholipid receptors: Signaling and biologyAnnu. Rev. Biochem.73,321-354(2004)
Kluk, M.J., and Hla, T.Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptorsBiochim. Biophys. Acta1582(1-3),72-80(2002)
