Mitoxantrone
Cat. No.：YN310218
| 产品名称: | Mitoxantrone |
| CAS No.: | 65271-80-9 |
| Chemical Name: | 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione; |
| Synonyms: | 米托蒽醌; mitozantrone |
| 分子量: | 444.48 |
| 分子式: | C₂₂H₂₈N₄O₆ |
| SMILES: | O=C1C2=C(C(NCCNCCO)=CC=C2NCCNCCO)C(C3=C(O)C=CC(O)=C13)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mitoxantrone是拓扑异构酶II (topoisomerase II)的抑制剂；也可抑制蛋白激酶C (PKC)，IC50值为8.5 μM。 |
| IC50和靶点: | [{name:"PKC:8.5 μM (IC50)'}, 'Topoisomerase II'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
McDonald, M., et al.: Drugs Exp. Clin. Res., 10, 745 (1984), Beijnen, J.H., et al.: Anal. Profiles Drug Subs., 17, 221 (1988),
