PKC-IN-1
Cat. No.：YN310298
CAS No. ：1046787-18-1
| 产品名称: | PKC-IN-1 |
| CAS No.: | 1046787-18-1 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 500.61 |
| 分子式: | C₂₅H₃₇FN₈O₂ |
| SMILES: | O=C(N1[C@@H](C)CN(CC2CCOCC2)[C@H](C)C1)N(C3)C(C)(C)C4=C3C(NC5=NC(C)=NC=C5F)=NN4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PKC-IN-1 是一种有效的，ATP-竞争性的，可逆的PKC抑制剂，对人 PKCβ 和 PKCα 的Ki值分别为 5.3 和 10.4 nM，对人 PKCα，PKCβI，PKCβII，PKCθ，PKCγ，PKC mu 和 PKCε 的IC50值分别为 2.3，8.1，7.6，25.6，57.5，314，808 nM。 |
| IC50和靶点: | [{name:"Human PKCα:2.3 nM (IC50)"},{name: "Human PKCβII:7.6 nM (IC50)"},{name: "Human PKCβI:8.1 nM (IC50)"},{name: "Human PKCθ:25.6 nM (IC50)"},{name: "Human PKCγ:57.5 nM (IC50)"},{name: "Human PKC mu:314 nM (IC50)"},{name: "Human PKCε:808 nM (IC50)"},{name: "Human PKCβ:5.3 nM (Ki)"},{name: "Human PKCα:10.4 nM (Ki)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
