Phorbol 12,13-dibutyrate
Cat. No.：YN310316
| 产品名称: | Phorbol 12,13-dibutyrate |
| CAS No.: | 37558-16-0 |
| Chemical Name: | Butanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl ester |
| Synonyms: | Phorbol dibutyrate; PDBu |
| 分子量: | 504.61 |
| 分子式: | C₂₈H₄₀O₈ |
| SMILES: | O=C1C(C)=C[C@@]2([H])[C@]3(O)[C@@]([C@@](C4(C)C)([H])[C@@]4(OC(CCC)=O)[C@H](OC(CCC)=O)[C@H]3C)([H])C=C(CO)C[C@]12O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Phorbol 12,13-dibutyrate (Phorbol dibutyrate) 是一种PKC激活剂和有效的皮肤肿瘤启动子。 |
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Geiges, D., Meyer, T., Marte, B., et al.Activation of protein kinase C subtypes α, γ, δ, ε, ζ, and η by tumor-promoting and nontumor-promoting agentsBiochem. Pharmacol.53(6),865-875(1997)
Rippmann, F.Hydrophobicity and tumor promoting activity of phorbol estersQuant. Struct.-Act. Relat.9(1),1-5(1990)
Scribner, J.D., and Boutwell, R.K.Inflammation and tumor promotion: Selective protein induction in mouse skin by tumor promotersEur. J. Cancer8(6),617-621(1972)
