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Daphnoretin

Cat. No.:YN310346

  • CAS No. :2034-69-7

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    • 生物活性
    • 参考文献
    • 产品名称: Daphnoretin
      CAS No.: 2034-69-7
      Chemical Name: 7-hydroxy-6-methoxy-3-[(2-oxo-2H-1-benzopyran-7-yl)oxy]-2H-1-benzopyran-2-one
      Synonyms:Dephnoretin; Thymelol
      分子量:352.29
      分子式:C₁₉H₁₂O₇
      SMILES:O=C1C(OC2=CC=C(C(O3)=C2)C=CC3=O)=CC4=CC(OC)=C(O)C=C4O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Daphnoretin (Dephnoretin) 是从Wikstroemia indica中提取得到的,拥有抗病毒活性。Daphnoretin 和PMA作用类似,可以直接激活蛋白激酶C,从而激活NADPH氧化酶。
      IC50和靶点:
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    • Feng, N.K.O., Chang, Y.L., Kuo, Y.H., et al.Daphnoretin, a new protein kinase C activator isolated from Wikstroemia indica C.A. MeyBiochem J.295(Pt 1),321-327(1993)

      Ho, W.-S., Xue, J.-Y., Sun, S.S.M., et al.Antiviral activity of daphnoretin isolated from Wikstroemia indicaPhytother. Res.24(5),657-661(2010)

      Gu, S., and He, J.Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cellsMolecules17(1),598-612(2012)

      Yu, S., Guo, H., Gao, X., et al.Daphnoretin: An invasion inhibitor and apoptosis accelerator for colon cancer cells by regulating the Akt signal pathwayBiomed. Pharmacother.111,1013-1021(2019)

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