Chelerythrine
Cat. No.:YN310357
产品名称: | Chelerythrine |
CAS No.: | 34316-15-9 |
Chemical Name: | |
Synonyms: | 白屈菜红碱 |
分子量: | 348.37 |
分子式: | C₂₁H₁₈NO₄ |
SMILES: | C[N+]1=CC2=C(OC)C(OC)=CC=C2C(C=CC3=C4)=C1C3=CC5=C4OCO5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Chelerythrine 是一种天然生物碱,为有效、选择性的 Ca2+/磷脂依赖性PKC拮抗剂,IC50值为 0.7 μM。Chelerythrine 具有抗肿瘤、抗糖尿病、抗炎的活性。Chelerythrine 抑制BclXL-Bak BH3肽结合,IC50为 1.5 μM,并从 BclXL 取代了 Bax。 Chelerythrine 诱导细胞凋亡和自噬。 |
IC50和靶点: | [{name:"PKC:0.7 μM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |