Decursinol angelate
Cat. No.：YN310363
| 产品名称: | Decursinol angelate |
| CAS No.: | 130848-06-5 |
| Chemical Name: | (2Z)-2-methyl-2-butenoic acid, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl ester |
| Synonyms: | 紫花前胡醇当归酯 |
| 分子量: | 328.36 |
| 分子式: | C₁₉H₂₀O₅ |
| SMILES: | C/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Decursinol angelate 是从Angelica gigas根部分离得到的一种细胞毒性物质，是PKC激酶的激活剂，拥有抗肿瘤和抗炎活性。 |
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Ahn, K.-S., Sim, W.-S., Lee, I.-K., et al.Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigasPlanta Med.63(4),360-361(1997)
Jiang, C., Guo, J., Wang, Z., et al.Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cellsBreast Cancer Res.9(6),R77(2007)
Abd El-Aty, A.M., Shah, S.S., Kim, B.M., et al.In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomesArch. Pharm. Res.31(11),1425-1435(2008)
Li, L., Li, W., Jung, S.-W., et al.Protective effects of decursin and decursinol angelate against amyloid β-protein-induced oxidative stress in the PC12 cell line: The role of Nrf2 and antioxidant enzymesBiosci. Biotech. Biochem.75(3),343-342(2011)
Choi, S.-S., Han, K.-J., Lee, J.-K., et al.Antinociceptive mechanisms of orally administered decursinol in the mouseLife Sci.73(4),471-485(2003)
