Cercosporin
Cat. No.：YN310370
| 产品名称: | Cercosporin |
| CAS No.: | 35082-49-6 |
| Chemical Name: | (13bR)-6,12-dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-5,11-dione |
| Synonyms: | 尾孢菌素 |
| 分子量: | 534.51 |
| 分子式: | C₂₉H₂₆O₁₀ |
| SMILES: | COC(C1=O)=C(C2=C3C(C4=C(C(OC)=C3CC(O)C)O)=C5C(OCOC6=C5C2=C1C(O)=C6)=CC4=O)CC(C)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cercosporin 由植物病原体Cercosporakikuchii和elsinochromes，elsinoe 家族真菌的色素产生。Cercosporin 是一种有效的光敏剂，具有短的活化波长，主要适用于表面PDT光动力研究 (尤其适用于避免穿孔的研究)。Cercosporin 是PKC的抑制剂，含有 PKC 活性所必需的醌结构特征, 其 IC50=0.6-1.3 μM。 |
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Shimpei, K., and Tamura, T.Cercosporin. A pigment of Cevcosporina kikuchii mafsumofo et tomoyasu. I. Cultivation of fungus, isolation and purification of pigmentJ. Am. Chem. Soc.79(21),5725-5726(1957)
Williamson, J.D., and Scandalios, J.G.Plant antioxidant gene responses to fungal pathogensTrends. Microbiol.1(6),239-245(1993)
Vandenbogaerde, A.L., Delaey, E.M., Vantieghem, A.M., et al.Cytotoxicity and antiproliferative effect of hypericin and derivatives after photosensitizationPhotochem. Photobiol.67(1),119-125(1998)
Morgan, B.J., Dey, S., Johnson, S.W., et al.Design, synthesis, and investigation of protein kinase C inhibitors: Total syntheses of (+)-calphostin D, (+)-phleichrome, cercosporin, and new photoactive perylenequinonesJ. Am. Chem. Soc.131(26),9413-9425(2009)
