TP0427736 hydrochloride
Cat. No.:YN460037
CAS No. :2459963-17-6
产品名称: | TP0427736 hydrochloride |
CAS No.: | 2459963-17-6 |
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分子量: | 暂无 |
分子式: | 暂无 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TP0427736 hydrochloride 是一种有效的ALK5激酶活性抑制剂,IC50为 2.72 nM,这种作用比对ALK3的抑制作用高 300 倍 (抑制ALK3的 IC50为 836 nM)。TP0427736 hydrochloride 还抑制由TGF-β1诱导的 A549 细胞中的 Smad2/3 磷酸化,IC50值为 8.68 nM。TP0427736 hydrochlor |
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