CID755673
Cat. No.：YN270153
CAS No. ：521937-07-5
| 产品名称: | CID755673 |
| CAS No.: | 521937-07-5 |
| Chemical Name: | 2,3,4,5-tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one |
| Synonyms: | 3-Hydroxy-5,6,7,8-tetrahydro-10-oxa-8-aza-benzo[a]azulen-9-one;2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one;7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one;CID 755673;CID-755673;7-Hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c] |
| 分子量: | 217.22 |
| 分子式: | C₁₂H₁₁NO₃ |
| SMILES: | O=C1NCCCC2=C1OC3=CC=C(O)C=C32 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CID755673是高效选择性的PKD1抑制剂，IC50of 值为182 nM。 |
| IC50和靶点: | [{name:"PKD1:182 nM (IC50)"},{name: "PKD3:227 nM (IC50)"},{name: "PKD2:280 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Rozengurt, E., Rey, O., and Waldron, R.T.Protein kinase D signalingJ. Biol. Chem.280(14),13205-13208(2005)
Sharlow, E.R., Giridhar, K.V., LaValle, C.R., et al.Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinoloneJ. Biol. Chem.283(48),33516-33526(2008)
