MA-0204
Cat. No.:YN290148
CAS No. :2095128-17-7
产品名称: | MA-0204 |
CAS No.: | 2095128-17-7 |
Chemical Name: | |
Synonyms: | (R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid;(3R)-3-Methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]imidazol-1-yl]methyl]phenoxy]hexanoic ac;MA-0204 |
分子量: | 476.49 |
分子式: | C₂₅H₂₇F₃N₂O₄ |
SMILES: | O=C(C[C@@H](CCCOC1=CC=CC=C1CN2C(C)=CN=C2C3=CC=C(C=C3)OC(F)(F)F)C)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MA-0204 是一种有效,高选择性,有口服活性的的过氧化物酶体增殖物激活受体 δ (PPARδ) 调节剂,对于人,小鼠和大鼠 PPARδ 的EC50分别为 0.4 nM、7.9 nM 和 10 nM。有研究 Duchene 肌营养不良症 (DMD) 的潜力。 |
IC50和靶点: | [{name:"PPARδ:0.4 nM (EC50, in human)"},{name: "PPARδ:7.9 nM (EC50, in mouse)"},{name: "PPARδ:10 nM (EC50, in rat)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |