GSK0660
Cat. No.：YN290187
CAS No. ：1014691-61-2
| 产品名称: | GSK0660 |
| CAS No.: | 1014691-61-2 |
| Chemical Name: | 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid, methyl ester |
| Synonyms: | GSK-0660，GSK 0660，GSK0660 |
| 分子量: | 418.49 |
| 分子式: | C₁₉H₁₈N₂O₅S₂ |
| SMILES: | O=C(C1=C(S(=O)(NC2=CC=C(NC3=CC=CC=C3)C=C2OC)=O)C=CS1)OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK0660是有效的PPARβ和PPARδ拮抗剂，IC50均为155 nM。 |
| IC50和靶点: | [{name:"PPARβ/δ:155 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Shearer, B.G., Steger, D.J., Way, J.M., et al.Identification and characterization of a selective peroxisome proliferator-activated receptor b/d (NR1C2) antagonistMol. Endocrinol.22(2),523-529(2008)
Palkar, P.S., Borland, M.G., Naruhn, S., et al.Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787Mol. Pharmacol.78(3),419-430(2010)
