iRucaparib-AP6
Cat. No.:YN290241
产品名称: | iRucaparib-AP6 |
CAS No.: | 2410557-00-3 |
Chemical Name: | |
Synonyms: | |
分子量: | 886.96 |
分子式: | C₄₆H₅₅FN₆O₁₁ |
SMILES: | O=C(NCC1)C2=CC(F)=CC3=C2C1=C(C4=CC=C(C=C4)CN(CCOCCOCCOCCOCCOCCOCCNC5=CC=CC(C(N6C7CCC(NC7=O)=O)=O)=C5C6=O)C)N3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | iRucaparib-AP6 是高效且特异的PARP1降解剂,基于 Rucaparib (PROTAC 的方法)。 iRucaparib-AP6 是一种 “非捕获性” PARP1 降解剂,可同时阻断 PARP1 的催化活性和支架作用。 |
IC50和靶点: | [{name:"PARP1:82 nM (DC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |