Ciprofibrate
Cat. No.：YN290508
| 产品名称: | Ciprofibrate |
| CAS No.: | 52214-84-3 |
| Chemical Name: | 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-propanoic acid |
| Synonyms: | 环丙贝特; Win35833 |
| 分子量: | 289.15 |
| 分子式: | C₁₃H₁₄Cl₂O₃ |
| SMILES: | CC(C)(OC1=CC=C(C2C(Cl)(Cl)C2)C=C1)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ciprofibrate (Win35833) 是一种有效的过氧化物酶体 (peroxisome) 增殖物，可增加 PPARalpha 的磷酸化水平。Ciprofibrate 是一种降血脂试剂，可用于原发性高脂血症的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Quang, T.H., Ngan, N.T.T., Minh, C.V., et al.Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldiiBioorg. Med. Chem. Lett.22(7),2527-2533(2012)
Forman, B.M., Chen, J., and Evans, R.M.Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δProc. Natl. Acad. Sci. USA94(9),4312-4317(1997)
Passilly, P., Jannin, B., Hassell, S.J., et al.Human HepG2 and rat Fao hepatic-derived cell lines show different responses to ciprofibrate, a peroxisome proliferator: analysis by flow cytometryExp. Cell. Res.223(2),436-442(1996)
Bighetti, E.J.B., Patricio, P.R., Casquero, A.C., et al.Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liverLipids Health Dis.8,50(2009)
