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Alkynyl myristic acid

Cat. No.:YN430262

  • CAS No. :82909-47-5

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    • 产品名称: Alkynyl myristic acid
      CAS No.: 82909-47-5
      Chemical Name: 13-tetradecynoic acid
      Synonyms:tetradec-13-ynoic acid,13-Tetradecyn-1-oic acid,13-Tetradecynoic acid
      分子量:224.34
      分子式:C₁₄H₂₄O₂
      SMILES:C#CCCCCCCCCCCCC(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Alkynyl myristic acid 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。
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    • Farazi, T.A., Waksman, G., and Gordon, J.I.The biology and enzymology of protein N-myristoylationJ. Biol. Chem.276(43),39501-39504(2001)

      Jiang, H., Khan, S., Wang, Y., et al.SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysineNature496,110-113(2013)

      Kolb, H.C., and Sharpless, K.B.The growing impact of click chemistry on drug discoveryDrug Discov. Today8(24),1128-1137(2003)

      Lutz, J.-F., and Zarafshani, Z.Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide-alkyne "click" chemistryAdv. Drug Deliv. Rev.60(9),958-970(2008)

      Vila, A., Tallman, K.A., Jacobs, A.T., et al.Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivativesChem. Res. Toxicol.21(2),432-444(2008)

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