A1874
Cat. No.:YN430077
产品名称: | A1874 |
CAS No.: | 2064292-12-0 |
Chemical Name: | |
Synonyms: | A-1874,A 1874 |
分子量: | 1173.59 |
分子式: | C₅₈H₆₂Cl₃F₂N₉O₇S |
SMILES: | ClC(C=C1)=CC=C1C2=N[C@H](C3=NN=C(C)N3C4=C2C(C)=C(C)S4)CC(NCCOCCOCCOCCNC(C5=CC(OC)=C(NC([C@H]6[C@H](C7=C(F)C(Cl)=CC=C7)[C@](C8=CC=C(Cl)C=C8F)(C#N)[C@H](CC(C)(C)C)N6)=O)C=C5)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | A1874 是一种以 nutlin 为基础的、BRD4-降解的 PROTAC,DC50值为 32 nM (诱导细胞内的 BRD4 降解)。有效抑制多种癌细胞增殖。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |