CP-10
Cat. No.:YN430104
产品名称: | CP-10 |
CAS No.: | 2366268-80-4 |
Chemical Name: | |
Synonyms: | |
分子量: | 871.94 |
分子式: | C₄₄H₄₉N₁₃O₇ |
SMILES: | CC(C(C1=O)=C(C)C2=CN=C(NC3=CC=C(N4CCN(CC5=CN(CCOCCNC6=CC=CC(C(N7C8CCC(NC8=O)=O)=O)=C6C7=O)N=N5)CC4)C=N3)N=C2N1C9CCCC9)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CP-10 是具有高选择性,特异性和显著的CDK6降解潜力 (DC50=2.1 nM) 的 PROTAC。它抑制几种造血细胞癌的增殖,包括多发性骨髓瘤,并且对突变和过表达的 CDK6 仍然可以降解。 |
IC50和靶点: | [{name:"CDK6:2.1 nM (DC50)'}, 'Cereblon'] |
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Clinical Trial: | |
Solvent & Solubility: |