XZ739
Cat. No.：YN430214
CAS No. ：2365172-19-4
规格
价格(RMB)
库存
| 产品名称: | XZ739 |
| CAS No.: | 2365172-19-4 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 1349.99 |
| 分子式: | C₆₅H₇₆ClF₃N₈O₁₂S₃ |
| SMILES: | O=C(C1=CC=C(N2CCN(CC3=C(C4=CC=C(Cl)C=C4)CCC(C)(C)C3)CC2)C=C1)NS(C5=CC(S(=O)(C(F)(F)F)=O)=C(N[C@@H](CSC6=CC=CC=C6)CCN(C)CCOCCOCCOCCNC7=C8C(C(N(C9CCC(NC9=O)=O)C8=O)=O)=CC=C7)C=C5)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | XZ739 是一种基于 CRBN 的PROTAC BCL-XL降解剂，作用于 MOLT-4 细胞，处理 16 小时后，DC50值为 2.5 nM。XZ739 还通过 caspase 介导的凋亡 (apoptosis) 诱导细胞死亡。 |
| IC50和靶点: | [{name:"Bcl-xL:2.5 nM (DC50)'}, 'Cereblon'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
