BSJ-04-132
Cat. No.：YN430224
CAS No. ：2349356-39-2
规格
价格(RMB)
库存
| 产品名称: | BSJ-04-132 |
| CAS No.: | 2349356-39-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 819.91 |
| 分子式: | C₄₂H₄₉N₁₁O₇ |
| SMILES: | O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(CCCCNC(COC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O)CC4)C=C3)N=C2N1C8CCCC8)N(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BSJ-04-132 是一种有效的，选择性的基于 Ribociclib (HY-15777) 的CDK4降解剂 (PROTAC)，对 CDK4/D1 和 CDK6/D1 的IC50分别为 50.6 nM 和 30 nM。BSJ-04-132 不诱导 CDK6 和 IKZF1/3 降解，具有抗癌活性。 |
| IC50和靶点: | [{name:"CDK4/D1:50.6 nM (IC50)"},{name: "CDK6/D1:30 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
