CRBN-6-5-5-VHL
Cat. No.:YN430225
产品名称: | CRBN-6-5-5-VHL |
CAS No.: | 2362575-45-7 |
Chemical Name: | |
Synonyms: | |
分子量: | 972.20 |
分子式: | C₅₁H₆₉N₇O₁₀S |
SMILES: | O=C(N1C(CCC2=O)C(N2)=O)C(C(C1=O)=CC=C3)=C3NCCCCCCOCCCCCOCCCCC(N[C@@H](C(C)(C)C)C(N(C[C@@H]4O)[C@@H](C4)C(NCC5=CC=C(C(SC=N6)=C6C)C=C5)=O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CRBN-6-5-5-VHL 是一种有效的选择性cereblon (CRBN)降解剂,DC50值为 1.5 nM,而对底物 IKZF1 和 IKZF3 的降解几乎没有影响。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |