Fusidic acid sodium salt
Cat. No.:YN251303
产品名称: | Fusidic acid sodium salt |
CAS No.: | 751-94-0 |
Chemical Name: | (4α,8α,9β,13α,14β)-16β-(acetyloxy)- 3α,11α-dihydroxy-29-nordammara-17Z(20),24-dien-21-oic acid, monosodium salt |
Synonyms: | 夫西地酸钠; Sodium fusidate; SQ-16360 |
分子量: | 538.69 |
分子式: | C₃₁H₄₇NaO₆ |
SMILES: | C[C@@H]([C@]1([H])CC[C@]([C@@](C[C@@H]/2OC(C)=O)3C)4C)[C@H](O)CC[C@]1(C)[C@]4([H])[C@H](O)C[C@@]3([H])C2=C(C(O[Na])=O)/CC/C=C(C)\C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Fusidic acid sodium salt (Sodium fusidate),Fusidium coccineum属甾体类抑菌抗生素,无皮质类固醇作用。Fusidic acid sodium salt通过阻止核糖体释放翻译延长因子G (EF-G) 来抑制细菌的生长。 |
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Verbist, L.The antimicrobial activity of fusidic acidJ. Antimicrob. Chemother.25(Suppl. B),1-5(1990)
Godtfredsen, W.O., Jahnsen, S., Lorck, H., et al.Fusidic acid: A new antibioticNature193,987(1962)
Savelsbergh, A., Rodnina, M.V., and Wintermeyer, W.Distinct functions of elongation factor G in ribosome recycling and translocationRNA15(5),772-780(2009)
Mohamed, M.F., and Seleem, M.N.Efficacy of short novel antimicrobial and anti-inflammatory peptides in a mouse model of methicillin-resistant Staphylococcus aureus (MRSA) skin infectionDrug Des. Devel. Ther.8,1979-1983(2014)