Parbendazole
Cat. No.：YN250243
CAS No. ：14255-87-9
| 产品名称: | Parbendazole |
| CAS No.: | 14255-87-9 |
| Chemical Name: | N-(6-butyl-1H-benzimidazol-2-yl)-carbamic acid, methyl ester |
| Synonyms: | SKF 29044 |
| 分子量: | 247.29 |
| 分子式: | C₁₃H₁₇N₃O₂ |
| SMILES: | O=C(OC)NC1=NC2=CC=C(CCCC)C=C2N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Parbendazole 是一种有效的microtubule重组抑制剂，能够破坏微管蛋白，EC50值为 8.79 nM，具有广谱的驱虫作用。 |
| IC50和靶点: | |
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Havercroft, J.C., Quinlan, R.A., and Gull, K.Binding of parbendazole to tubulin and its influence on microtubules in tissue-culture cells as revealed by immunofluorescence microscopyJ. Cell Sci.49,195-204(1981)
Lo, Y.-C., Senese, S., France, B., et al.Computational cell cycle profiling of cancer cells for prioritizing FDA-approved drugs with repurposing potentialSci. Rep.7(1),(2017)
Charles, T.P., Pompeu, J., and Miranda, D.B.Efficacy of three broad-spectrum anthelmintics against gastrointestinal nematode infections of goatsVet. Parasitol.34(1-2),71-75(1989)
