MMV008138
Cat. No.:YN250338
CAS No. :1679333-73-3
产品名称: | MMV008138 |
CAS No.: | 1679333-73-3 |
Chemical Name: | |
Synonyms: | |
分子量: | 361.22 |
分子式: | C₁₈H₁₄Cl₂N₂O₂ |
SMILES: | O=C([C@@H]1CC2=C([C@@H](C3=CC=C(Cl)C=C3Cl)N1)NC4=C2C=CC=C4)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MMV008138 是一种选择性 2-C-甲基-d-赤藓糖醇4-磷酸胞苷酰转移酶(IspD)靶向抗疟药, 对PfIspD(P. falciparumIspD) 作用的IC50值为 44 nM。MMV008138 抑制对恶性疟原虫 Dd2 虫株生长的 IC50值为 250 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |