Albendazole sulfoxide
Cat. No.：YN250402
| 产品名称: | Albendazole sulfoxide |
| CAS No.: | 54029-12-8 |
| Chemical Name: | N-[6-(propylsulfinyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Synonyms: | Ricobendazole; Albendazole oxide |
| 分子量: | 281.33 |
| 分子式: | C₁₂H₁₅N₃O₃S |
| SMILES: | O=C(OC)NC1=NC2=CC=C(S(CCC)=O)C=C2N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Albendazole sulfoxide (Ricobendazole) 是Albendazole 的主要代谢物，具有抗寄生虫活性 (e.g.Echinococcus multilocularis)。 |
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Adas, G., Arikan, S., Kemik, O., et al.Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)World J. Gastroenterol.15(1),112-116(2009)
Baliharová, V., Velík, J., Fimanová, K., et al.Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitroPharmacol. Rep.57,97-106(2005)
Katiyar, S.K., and Edlind, T.D.In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivativesAntimicrob. Agents and Chemother.41(12),2729-2732(1997)
Ridoux, O., and Drancourt, M.In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolitesAntimicrob. Agents and Chemother.42(12),3301-3303(1998)
Morgan, U.M., Reynoldson, J.A., and Thompson, R.C.A.Activities of several benzimidazoles and tubulin inhibitors against Giardia spp. in vitroAntimicrob. Agents Chemother.37(2),328-331(1993)
Palomares, F., G., P., Pérez, R., et al.In vitro effects of albendazole sulfoxide and praziquantel against Taenia solium and Taenia crassiceps cystsAntimicrob. Agents and Chemother.48(6),2302-2304(2004)
Cai, Z.Y., Galettis, P., Lu, Y., et al.Pharmacokinetics of albendazole in New Zealand white rabbits: Oral versus intraperitoneal administrationAnticancer Res.27,417-422(2007)
