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Pafuramidine

Cat. No.:YN250614

  • CAS No. :186953-56-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Pafuramidine
      CAS No.: 186953-56-0
      Chemical Name: 4,4′-(2,5-furandiyl)bis[N-methoxy-benzenecarboximidamide
      Synonyms:DB289
      分子量:364.40
      分子式:C₂₀H₂₀N₄O₃
      SMILES:N=C(C1=CC=C(C2=CC=C(C3=CC=C(C(NOC)=N)C=C3)O2)C=C1)NOC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Pafuramidine (DB289)是口服生物相容性的furamidine原药,具有抗肺囊虫肺炎活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Boykin, D.W., Kumar, A., Hall, J.E., et al.Anti-pneumocystis activity of bis-amidoximes and bis-o-alkylamidoximes prodrugsBioorganic Med. Chem. Lett.6(24),3017-3020(1996)

      de Gama Jaén Batista, D., Batista, M.M., de Oliveira, G.M., et al.Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivoPLoS One6(7),e22155(2011)

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