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Fluralaner

Cat. No.:YN250687

  • CAS No. :864731-61-3

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    • 生物活性
    • 参考文献
    • 产品名称: Fluralaner
      CAS No.: 864731-61-3
      Chemical Name: 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-benzamide
      Synonyms:A1443; AH252723
      分子量:556.29
      分子式:C₂₂H₁₇Cl₂F₆N₃O₃
      SMILES:O=C(NCC(NCC(F)(F)F)=O)C1=CC=C(C2=NOC(C(F)(F)F)(C3=CC(Cl)=CC(Cl)=C3)C2)C=C1C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fluralaner (INN)是一种全身性杀虫剂和杀螨剂,通过有效阻断GABA和L-glutamate氯化物通道。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Ozoe, Y., Asahi, M., Ozoe, F., et al.The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels.Biochem. Biophys. Res. Commun.391(1),744-749(2010)

      Gassel, M., Wolf, C., Noack, S., et al.The novel isoxazoline ectoparasiticide fluralaner: Selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity.Insect Biochem. Mol. Biol.45,111-124(2014)

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