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Toltrazuril (sulfone)

Cat. No.:YN250690

  • CAS No. :69004-04-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Toltrazuril (sulfone)
      CAS No.: 69004-04-2
      Chemical Name: 1-methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfonyl]phenoxy]phenyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
      Synonyms:妥曲珠利砜; Ponazuril
      分子量:457.38
      分子式:C₁₈H₁₄F₃N₃O₆S
      SMILES:O=S(C1=CC=C(C=C1)OC2=C(C=C(C=C2)N3C(N(C(NC3=O)=O)C)=O)C)(C(F)(F)F)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Toltrazuril sulfone (Ponazuril) 是 Toltrazuril (HY-B0175 ) 的代谢物,具有抗原生动物活性。Toltrazuril sulfone 是一种三嗪类抗球虫剂,被开发用于预防家禽球虫病。
      IC50和靶点:
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      In Vivo:
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    • Benoit, E., Buronfosse, T., Moroni, P., et al.Stereoselective S-oxygenation of an aryl-trifluoromethyl sulfoxide to the corresponding sulfone by rat liver cytochromes P450Biochem. Pharmacol.46(12),2337-2341(1993)

      Mitchell, S.M., Zajac, A.M., Davis, W.L., et al.Efficacy of ponazuril in vitro and in preventing and treating Toxoplasma gondii infections in miceJ. Parasitol.90(3),639-642(2004)

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