Doramectin
Cat. No.:YN250698
产品名称: | Doramectin |
CAS No.: | 117704-25-3 |
Chemical Name: | 25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-avermectin A1a |
Synonyms: | 多拉菌素 |
分子量: | 899.11 |
分子式: | C₅₀H₇₄O₁₄ |
SMILES: | CO[C@@H]1[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](OC)C2)[C@H](C)O[C@@]([H])(O[C@H](/C(C)=C/C[C@]3([H])C[C@]([H])(OC4=O)C[C@]5(C=C[C@H](C)[C@@H](C6CCCCC6)O5)O3)[C@@H](C)/C=C/C=C7CO[C@@]8([H])[C@]\7(O)[C@@]4([H])C=C(C)[C@H]8O)C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Doramectin 是 Ivermectin (HY-15310) 的衍生物。Doramectin 是一种有效的抗寄生虫抗生素。Doramectin 具有在 NMRI 小鼠感染模型中抗曼氏链球菌作用。 |
IC50和靶点: | |
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Holden-Dye, L., and Walker, R.J.Anthelmintic drugs and nematicides: Studies in Caenorhabditis elegansWormBook16,1-29(2014)
Michael, B., Meinke, P.T., and Shoop, W.Comparison of ivermectin, doramectin, selamectin, and eleven intermediates in a nematode larval development assayJ. Parasitol.87(3),692-696(2001)