Mefloquine hydrochloride
Cat. No.：YN250723
| 产品名称: | Mefloquine hydrochloride |
| CAS No.: | 51773-92-3 |
| Chemical Name: | rel-αS-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol, monohydrochloride |
| Synonyms: | Mefloquin hydrochloride |
| 分子量: | 414.77 |
| 分子式: | C₁₇H₁₇ClF₆N₂O |
| SMILES: | O[C@H]([C@]1([H])NCCCC1)C2=CC(C(F)(F)F)=NC3=C(C(F)(F)F)C=CC=C32.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mefloquine hydrochloride 为抗疟疾化合物。 |
| IC50和靶点: | |
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Ohnmacht, C.J., Patel, A.R., and Lutz, R.E.Antimalarials. 7. Bis(trifluoromethyl)-α-(2-piperidyl)-4-quinolinemethanolsJ. Med. Chem.14(10),926-928(1971)
Combrinck, J.M., Mabotha, T.E., Ncokazi, K.K., et al.Insights into the role of heme in the mechanism of action of antimalarialsACS Chem Biol.8(1),133-137(2013)
Grabias, B., and Kumar, S.Adverse neuropsychiatric effects of antimalarial drugsExpert Opin. Drug Saf.15(7),903-910(2016)
Holden, J.M., Slivicki, R., Dahl, R., et al.Behavioral effects of mefloquine in tail suspension and light/dark testsSpringerplus4:702,(2015)
