Closantel sodium
Cat. No.:YN250769
产品名称: | Closantel sodium |
CAS No.: | 61438-64-0 |
Chemical Name: | N-[5-Chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-benzamide Monosodium Salt; |
Synonyms: | 氯氰碘柳胺钠 |
分子量: | 685.06 |
分子式: | C₂₂H₁₃Cl₂I₂N₂NaO₂ |
SMILES: | O=C(NC1=CC(Cl)=C(C(C2=CC=C(Cl)C=C2)C#N)C=C1C)C3=CC(I)=CC(I)=C3O[Na] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Closantel sodium 是有效的抗寄生虫活性的卤化水杨酰苯胺。Closantel sodium 是一种有效且高度特异性的盘尾丝虫几丁质酶 (OvCHT1) 抑制剂,IC50为 1.6 μM,Ki为 468 nM。Closantel sodium 抑制了食蟹曲霉 L3 至 L4 的蜕皮。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Van Gyseghem, E., et al.: J. Pharm. Biomed. Anal., 41, 751 (2006), De Spiegeleer, B., et al.: J. Pharm. Biomed. Anal., 44, 254 (2007), Fleischer, R., et al.: J. Biol. Chem., 282, 8583 (2007), Borgsteede, F., et al.: Vet. Parasitol., 155, 235 (2008),