Clorsulon
Cat. No.：YN251065
CAS No. ：60200-06-8
| 产品名称: | Clorsulon |
| CAS No.: | 60200-06-8 |
| Chemical Name: | 4-amino-6-(1,2,2-trichloroethenyl)-1,3-benzenedisulfonamide |
| Synonyms: | 氯舒隆; L631529; MK401 |
| 分子量: | 380.66 |
| 分子式: | C₈H₈Cl₃N₃O₄S₂ |
| SMILES: | O=S(C1=C(/C(Cl)=C(Cl)\Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clorsulon (L631529; MK401) 是一种具有口服活性的灭虫试剂 (flukicidal agent)，用于犊牛和羊的肝吸虫 (Fasciolahepatica和Fasciolagigantica) 感染。Clorsulon 也是 3-磷酸甘酸酯和 ATP 的竞争性抑制剂，在体外可抑制成熟肝片吸虫对葡萄糖的利用以及乙酸和丙酸的形成。 |
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Meaney, M., Fairweather, I., Brennan, G.P., et al.Fasciola hepatica: Effects of the fasciolicide clorsulon in vitro and in vivo on the tegumental surface, and a comparison of the effects on young- and old-mature flukesParasitol. Res.91(3),238-250(2003)
Sundlof, S.F., Bliss, E.L., Greiner, E.C., et al.Efficacy of clorsulon for the treatment of experimentally induced infections of fasciola hepatica in goatsAm. J. Vet. Res.52(1),111-114(1991)
Zimmerman, G.L., Wallace, D.H., Schons, D.J., et al.Efficacy of clorsulon against mature naturally acquired fasciola hepatica infections in cattle and sheepAm. J. Vet. Res.47(8),1665-1667(1986)
