Moxidectin
Cat. No.:YN251132
产品名称: | Moxidectin |
CAS No.: | 113507-06-5 |
Chemical Name: | (6R,23E,25S)-5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)-milbemycin B |
Synonyms: | 莫西菌素; CL301423 |
分子量: | 639.82 |
分子式: | C₃₇H₅₃NO₈ |
SMILES: | C/C([C@H]([C@H](/C1=N/OC)C)O[C@]2(C1)C[C@](OC([C@@](C=C(C)[C@@H](O)[C@@]3([H])OC/C4=C\C=C\[C@H](C)C5)([H])[C@@]34O)=O)([H])C[C@](C/C=C5\C)([H])O2)=C\C(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Moxidectin(ProHeart 6; CL301423; Cydectin)是驱虫剂,可用于预防和控制心丝虫和蛔虫。 |
IC50和靶点: | |
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Kumar, A., Byun, H.S., Bittman, R., et al.The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent mannerCell. Signal.23(7),1144-1152(2011)
Ranjan, S., Trudeau, C., Prichard, R.K., et al.Efficacy of moxidectin against naturally acquired nematode infections in cattleVet. Parasitol.41(3-4),227-231(1992)
Ménez, C., Sutra, J.-F., Prichard, R., et al.Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activityPLoS Negl. Trop. Dis.6(11),e1883(2012)